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Health Sciences Authority

FY 2010/11

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Research Publications

Apr 2010 to Mar 2011

Please click here to view more details of the publications.

Health Products Regulation Group

Title of Paper Author(s)
H1N1 Vaccination and Pharmacovigilance in Singapore Sally Soh, Tan Wei Chuen, Belinda Tan, Adena Lim, Dorothy Toh, Chan Cheng Leng
Post-vaccination abscesses requiring surgical drainage in a tertiary children's hospital in Singapore N.W.H. Tan, W.J. Pan, H.H.B.M. Yunos, Wei Chuen Tan, K.B.L. Lim. 
Safety monitoring of H1N1 vaccines in Singapore during the H1N1 pandemic Chan Cheng Leng, Sally Soh, Dorothy Toh 
Case Study: A cluster of serious adverse reaction caused by illegal aphrodisiac products Vigilance Branch (HPRG)
Inter-ethnic Comparisons of Important Pharmacology Genes Using Single Nucleotide Polymorphism Databases: Potential Application to Drug Regulatory Assessments Jieming Chen (Genome Institute of Singapore), Yik Ying Teo (Department of Statistics & Applied Probability, National University of Singapore), Dorothy SL Toh, Cynthia Sung 
ADR News: April 2010 Vigilance Branch and Pharmacovigilance Advisory Committee (PVAC)
ADR News: August 2010 Vigilance Branch and Pharmacovigilance Advisory Committee (PVAC)
ADR News: December 2010 Vigilance Branch and Pharmacovigilance Advisory Committee (PVAC)

Blood Services Group

Title of Paper Author(s)
Effect of missing killer-immunoglobulin-like receptor ligand in recipients undergoing HLA full matched, non-T-depleted sibling donor transplantation: a single institution experience of 151 Asian patients Linn YC, Phang CY, Lim TJ, Chong SF, Heng KK, Lee JJ, Loh Y, Hwang W, Goh YT, Koh M
Emerging natural cell killer immunotherapies: large-scale ex vivo production of highly potent anticancer effectors Dr Garnet Suck & Dr Mickey Koh
KHYG-1 and NK-92 represent different subtypes of LFA-1- mediated NK cell adhesiveness Dr Garnet Suck, Dr Suet-Mien Tan, Selina Chu, Madelaine Niam, Ardcharaporn Vararattanavech, Tsyr Jong Lim, and Dr Mickey Koh
IRF8 and IRF3 cooperatively regulate rapid interferon-{beta} induction in human blood monocytes Li P, Wong JJ, Sum C, Sin WX, Ng KQ, Koh MB, Chin KC

Applied Sciences Group

Title of Paper Author(s)
Analytical toxicological screening and quantification of drugs and metabolites in biological fluids by LC–TOF-MS Teo Kay Wah, Tang Bi Ying, Danny Lo Siaw Teck, Yao Yi Ju
Isolation and structure elucidation of an interaction product of aminotadalafil found in an illegal health food product Adrian Häberli, Philippe Girard, Min Yong Low, Xiaowei Ge
Discriminating authentic Nostoc flagelliforme from its counterfeits by applying alternative ED-XRF and FTIR techniques Angela Li, Yun Wei Yat, Wee Kim Yap, Chee Wei Lim, Sheot Harn Chan 
Characterization of Chinese Medicines by Comprehensive Two-Dimensional Gas Chromatography and Time-of-Flight Mass Spectrometry (GC×GC-TOFMS) with Assistance of Multivariate Data Analyses Tan Jing , Li Lin, Zeng Yun , Ge Xiaowei , Low Min Yong

Research Projects

Apr 2010 to Mar 2011

Please click here to download the projects details in pdf.

Blood Services Group

Title of Research Project Principal Investigator(s)
Molecular Typing of Diego Blood Groups Ian Loke, Dr Marieta Chan, Michael Ng 
LFA-1 integrin involvement in NK-92 and KHYG-1 – manuscript is currently submitted to the Journal Cytotherapy  Dr.Garnet Suck, Dr. Tan Suet Mien, and Dr. Mickey Koh 
Molecular study of highly potent CD56+CD8+ NK cells: implications for cancer cellular therapy  Dr.Garnet Suck, Ho Seih Hwa, and Dr. Mickey Koh
Study of Risk factors for Vasovagal Reaction amongst Blood Donors in Singapore Dr Jason Chay Wai Mun, Dr Diana Teo Lay Tin, Dr Tan Hwee Huang, , Toh Ching Lian, Ruzanah Binte Othman, Chong Jye Ling, Kyaw Phone Myint 
Prevalence of West Nile Virus in Singapore Blood Donors Shu Pei Huey, Ng Kooi Sim, Chua Sze Sze, Sally Lam, and Dr. Diana Teo
Syphilis Screening using Serodia – TPPA Auto on Olympus PK7300 System Shu Pei Huey and Chua Sze Sze
Evaluation of Procleix ULTRIO Plus Assay Test Kit Ng Kooi Sim, Jeslyn Tan Wan Cheng and Chua Sze Sze
Who gets Cryoprecipitate? Dr. Ramir Alcantara, Dr. San Ky Ky, Dr. Ng Heng Joo and Dr. Mickey Koh
Effect of missing killer-immunoglobulin-like receptor ligand in recipients undergoing HLA full matched, non-T-depleted sibling donor transplantation: a single institution experience of 151 Asian patients. Dr. Linn Yeh Ching, Phang Chew Yen, Lim Tsyr Jong, Chong SF, Heng KK, Lee JJ, Loh Y, Dr. William Hwang, Dr. Goh Yeow Tee, Dr. Mickey Koh
Discrepant serologic ABO typing in an unusual Para-Bombay ABh sample caused by compound heterozygosity for different FUT1 mutations Dr. Ramir Alcantara, Dr. Mickey Koh, Marilyn Moulds, Jennifer Haywood, Annika Hult, Dr. Martin Olsson, Dr. Storry Jill
Study on factors leading to bruising and haematoma in apheresis Rohadiah Bte Ramli, Ruzanah Bte Othman, Toh Ching Lian, Dr Tan Hwee Huang, Dr Diana Teo
The Investigation of Clinically Significant Alloantibodies in Warm Autoimmune Haemolytic Anaemia (WAIHA) Using Differential Adsorption Technique Kang Kok Sheng, Michael Ng
The Use of Techno Twinstation for Routine Blood Grouping. Is This Automated Blood Bank Instrument Truly a Walk-Away Unit? Siti Salbiah Bte Masnor, Michael Ng, Dr. Diana Teo
Improving The Method Of Platelet Sample Collection Noorhayati Rahamat, Debbie Pennefather
The Impact of Implementation of the H1N1-related Deferral Criteria on Blood Donors in Singapore Nwe Ni Aung and Dr. Tan Hwee Huang
Frequency of Jk3 among Singapore Blood Donors Michael Ng and Amjad
Comparative study of the INTERCEPT PCT and MIASOL PRT systems on the inactivation of DENV and CHIKV in Single-Donor Platelet Concentrates Tan Fang Hui, Sally Lam, Low Swee Ling and Dr. Tan Li Kiang
Seroprevalence of Dengue in Singapore Tan Yi Wen, Annabel Ang, Sally Lam, Sharon Goh and Dr. Tan Li Kiang

Applied Sciences Group

Title of Research Project Principal Investigator(s)
High Throughput Analysis of Western Drug Adulterants in Herbal Products by Rapid Resolution Liquid Chromatography Sharon Oh Sze Yin, Dr Ge Xiaowei, Angela Ee, Koh Hui Shi & Jessie Teo 
FTIR-ATR Library for Primary Standards in Pharmaceutical Laboratory Dr Kee Chee Leong, Dr Ge Xiaowei, Charmaine Ang Geok Hoon & Len Shea Mei 
Electronic Cigarette – Study of Harmful Substances Cheah Nuan Ping, Chung Loi Hian & Faridatul Akmam Morsed 
Mass Chromatographic Determination of Benzo[a]pyrene in Mainstream Cigeratte Smoke Cheah Nuan Ping & Faridatul Akmam Morsed 
Use of IRMS for Counterfeit Cialis Samples Yong Yuk Lin, Yeo Wee Chuan, Fiona Chen & Lim Chin Chin 
Development of a Master Database for Counterfeit Drugs Lim Thiam Bon, Pan Xinghua, Yong Yuk Lin & Lim Chin Chin