print small large

This application is a service of the Singapore Government.

Health Sciences Authority

Certified Reference Materials

Chemical Metrology bottles

CML produces pure substance CRMs as calibrants. Matrix CRMs are also produced for quality control and validation of methods. A comprehensive Certificate of Analysis is provided with each CRM.

Certified Reference Materials

Pure Substance Certified Reference Materials


  1. HRM-1002A: Benzoic acid
  2. HRM-1003A: Methyl paraben
  3. HRM-1004A: n-Butyl paraben
  4. HRM-1018A: Sorbic acid

Artificial Sweeteners

  1. HRM-1009A: Sodium cyclamate
  2. HRM-1010A: Saccharin
  3. HRM-1012A: Acesulfame potassium
  4. HRM-1015A: Sucralose
  5. HRM-1019A: Aspartame


  1. HRM-1016A: Carbamazepine

Amino Acids

  1. HRM-1006A: L-Valine
  2. HRM-1007A: L-Proline
  3. HRM-1008A: L-Leucine
  4. HRM-1013A: L-Isoleucine
  5. HRM-1014A: L-Phenylalanine


  1. HRM-1017A: Benzo[a]pyrene


Matrix Certified Reference Materials

  1. HRM-2003A: Trace and essential elements (As, Ca, Cd & Pb) in mushroom powder
  2. HRM-2006A: Toxic elements (As, Hg & Pb) in cosmetic cream
  3. HRM-2008A: Trace elements (Cd, Pb, As & As Species) in apple juice
  4. HRM-2009A: Trace elements (Al, As, Ca, Cd, Cr, Cu, Mo, Ni & Pb) in water


Clinical Certified Reference Materials

  1. HRM-2002A: Calcium, potassium and sodium in frozen human serum
  2. HRM-2005A: Calcium, potassium, sodium, magnesium, iron & chloride in frozen human serum
  3. HRM-2011A: Sodium, chloride, copper, selenium and phosphorous in frozen human serum
  4. HRM-3002B: Creatinine, glucose, total cholesterol, total glycerides, free glycerol, HDL-cholesterol, LDL-cholesterol, urea and uric acid in frozen human serum
  5. HRM-3003A: Haemoglobin A1c in human blood
  6. HRM-3003B: Haemoglobin A1c in human blood


Click here to view our flyer for clinical CRMs

For enquiries on CRMs, please contact CML at

Customers from the Republic of Korea may contact our distributor for the purchase of the CRMs:

Fore Front Test Co. Ltd

KRANZ Techno 702, Doonchon-dero 388, joongwon-gu, Seongnam-si, Gyeonggi-do, South Korea, Zip Code 13403

Contact Person : Dr Jang-Hyuk Ahn

E-mail :

Tel : +82-31-734-7155

Fax : +82-31-734-7156