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This application is a service of the Singapore Government.

Health Sciences Authority

Scope of Service


Scope of Service

The Biology Division offers the following main areas of service:

1. Examination of Exhibits for Biological Fluids

Items may be screened for the presence of biological fluids (blood, semen, and saliva). The Laboratory provides both presumptive and confirmatory tests. Presumptive tests indicate the presence of a particular body fluid whereas confirmatory tests involve additional procedures to conclusively identify a body fluid. Tests for blood can include detection of the catalytic properties of heme and haemoglobin. The tests for semen include presence of acid phosphatase, prostate specific antigen, semenogelin, and microscopic identification of spermatozoa.

2. Forensic DNA Profiling

The current technology used for DNA profiling worldwide is the amplification of Short Tandem Repeat loci by Polymerase Chain Reaction (STR-PCR) followed by detection via capillary electrophoresis. The STR-PCR approach offers a rapid and sensitive technique, especially suitable for the limited and degraded samples commonly encountered in crime casework. The DNA Profiling Laboratory currently offers testing based on 21 STR loci.

3. Kinship Testing for Criminal Investigations

Criminal investigations requiring biological relationship evidence usually revolve around “product of conception (POC)” cases resulting from rape or incest. DNA tests can be conducted to establish the identity of the putative father. Biological relationship information can also prove helpful in cases of unidentified human remains.

4. Forensic DNA Database Management and Consultancy