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Health Sciences Authority
Dear Healthcare Professional Letters

Communication on the association of MabThera® (Rituximab) with fatal infusion related reactions in patients with Rheumatoid arthritis

Audiences

Healthcare professional

Product type

Therapeutic Products

6 May 2011

This article has been migrated from an earlier version of the site and may display formatting inconsistencies.

Roche, in consultation with HSA, is informing healthcare professionals about new safety information on the use of MabThera®(Rituximab) in rheumatoid arthritis. Since the marketing approval of MabThera® for use in rheumatoid arthritis, Roche has received postmarketing reports of fatal infusion related reactions with the use of the medicine. Healthcare professionals are advised to follow the recommendations provided in this Dear Healthcare Professional Letter when using the product, including being vigilant for signs of hypersensitivity or anaphylaxis.


Only abstracts of the Dear Healthcare Professional Letters (DHCPL) are provided on this website. Details of these letters can be found in the MOH Alert System, which is accessible via the Health Professionals Portal (HPP), a one-stop portal for all healthcare professionals in Singapore. Dentists, medical doctors and pharmacists may access HPP at https://hpp.moh.gov.sg and follow the procedures below to access the MOH Alert system.

Step 1: Select your profession under ‘For Healthcare Professionals’.

Step 2: Click on ‘Useful links’.

Step 3: Click on ‘MOH Alert’ and log in via Singpass.

Step 4: Click on ‘Drug Alerts’ or ‘Med Device Alerts’ to view the DHCPLs.

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