Voluntary recall of IKERVIS EYE DROPS, EMULSION 1MG/ML (SIN15216P), lot number 1L49P due to possible decrease in efficacy

A Dear Healthcare Professional Letter has been issued by Santen Pharmaceutical Asia Pte Ltd to inform healthcare professionals of the voluntary recall of one lot of IKERVIS EYE DROPS, EMULSION 1MG/ML, Lot 1L49P due to possible decrease in product efficacy. During routine stability studies, it was found that the affected batch of lkervis did not meet the ciclosporin A (CsA) targeted concentration and presented a lower CsA concentration due to crystallisation of the CsA. Healthcare professionals are advised to stop using the affected batch and to review their patients that were on the affected batch of the eyedrops. Please refer to the letter for details.

Only abstracts of the Dear Healthcare Professional Letters (DHCPL) are provided on this website. Details of these letters can be found in the MOH Alert System, which is accessible via the Health Professionals Portal (HPP), a one-stop portal for all healthcare professionals in Singapore. Dentists, medical doctors and pharmacists may access HPP at https://hpp.moh.gov.sg and follow the procedures below to access the MOH Alert system.

Step 1: Select your profession under ‘For Healthcare Professionals’.

Step 2: Click on ‘Useful links’.

Step 3: Click on ‘MOH Alert’ and log in via Singpass.

Step 4: Click on ‘Drug Alerts’ or ‘Med Device Alerts’ to view the DHCPLs.