Voluntary recall – Zerbaxa® (ceftolozane/tazobactam) due to manufacturing issue

A Dear Healthcare Professional Letter has been issued by MSD Pharma (Singapore) to inform healthcare professionals of the recall of Zerbaxa^® for injection (1.5 g) 1g/0.5g 10×20ml vial. Due to a recent routine testing, the results of sterility tests of seven batches of product were out of specification. These seven batches have not been released into the market. While these products distributed to the market had met the registered release specifications, they were manufactured on the same equipment as the affected batches. As a result, MSD is conducting a voluntary recall of all Zerbaxa® injections within expiry. Healthcare professionals are advised to discontinue the use of Zerbaxa® and consider alternative treatment plans for their patients. Please refer to the letter for details.

Only abstracts of the Dear Healthcare Professional Letters (DHCPL) are provided on this website. Details of these letters can be found in the MOH Alert System, which is accessible via the Health Professionals Portal (HPP), a one-stop portal for all healthcare professionals in Singapore. Dentists, medical doctors and pharmacists may access HPP at https://hpp.moh.gov.sg ↗ (opens in new tab) and follow the procedures below to access the MOH Alert system.

Step 1: Select your profession under ‘For Healthcare Professionals’.

Step 2: Click on ‘Useful links’.

Step 3: Click on ‘MOH Alert’ and log in via Singpass.

Step 4: Click on ‘Drug Alerts’ or ‘Med Device Alerts’ to view the DHCPLs.