PRISM (Poisons, controlled drugs and psychotropics)

The PRISM e-service gives users the convenience of carrying out transactions with HSA, and to search for related information online.

Last updated 30 April 2026

Ensure you have the following before you access the PRISM e-service:

CRIS company account
Corppass

PRISM helpdesk

If you encounter technical issues with PRISM e-services (e.g. unable to upload documents in PRISM or CRIS), please e-mail the HSA helpdesk with the screenshot of the error message or call 6776 0168 (from 7.00 am to midnight daily) for assistance.

Make an application - apply@prism

E-services	User guide
Apply for Form A Poisons Licence	User guide [PDF, 1.5 MB]
Apply for licence to import controlled drugs	User guide [PDF, 745 KB]
Apply for licence to sell controlled drugs by wholesale	User guide [PDF, 750 KB]
Apply for licence to export controlled drugs	User guide [PDF, 747 KB]
Apply for licence to manufacture or assemble controlled drugs	User guide [PDF, 1.7 MB]
Apply for confirmation of authorisation to import a psychotropic substance/approval to import therapeutic products containing psychotropic substances	User guide [PDF, 1.1 MB]
Apply for export licence for psychotropic substances/approval to export therapeutic products containing psychotropic substances	User guide [PDF, 1.2 MB]
Apply for confirmation of authorisation to import a restricted substance/certificate of approval for import of a therapeutic product	User guide [PDF, 1 MB]

Withdraw application - withdraw@prism

E-services	User guide
Withdraw application for Form A Poisons Licence	User guide [PDF, 233 KB]
Withdraw application for a licence to sell controlled drugs by wholesale	User guide [PDF, 230 KB]
Withdraw application for a licence to manufacture or assemble controlled drugs	User guide [PDF, 233 KB]

Cancel licence - cancel@prism

E-services	User guide
Cancel Form A Poisons Licence	User guide [PDF, 297 KB]
Cancel licence to sell controlled drugs by wholesale	User guide [PDF, 254 KB]
Cancel licence to manufacture or assemble controlled drugs	User guide [PDF, 297 KB]

Amend registration or licence - amend@prism

E-services	User guide
Amend Form A Poisons Licence	User guide [PDF, 1.3 MB]
Amend licence to sell controlled drugs by wholesale	User guide [PDF, 934 KB]
Amend licence to manufacture or assemble controlled drugs	User guide [PDF, 1.6 MB]
Amend company information
Amend applicant's details for licences and applications (Not applicable for Form A Poisons Licence and licence to sell controlled drugs by wholesale)

Renew licence - renew@prism

E-services	User guide
Renew Form A Poisons Licence	User guide [PDF, 601 KB]
Renew licence to sell controlled drug by wholesale	User guide [PDF, 722 KB]
Renew licence to manufacture or assemble controlled drugs	User guide [PDF, 601 KB]
Auto renewal preference