Genotropin (Somatropin): Importance of following Instructions For Use to mitigate potential defect in pre-filled pen device that could result in a increase in the dosage administered

Pfizer Private Limited would like to inform healthcare professionals of a potential manufacturing defect in the dosing mechanic of some GoQuick pre-filled pens used to administer Genotropin. The manufacturing defect was found to create the possibility of the dose being set to one extra click beyond the dose selected and indicated in the memory window in some pens when the patient turns the knob with excessive force. This may result in a small increase in the dosage administered compared to the preset dose. Healthcare professionals are advise to remind their patients to follow the instructions in the Patient Information Leaflet, which shows the way in which patients should set the correct dose. Please refer to the letter for more information.

 
 
Healthcare professional, Therapeutic Products
Published:

Dear Healthcare Professional Letters

12 Dec 2019

Only abstracts of the Dear Healthcare Professional Letters (DHCPL) are provided on this website. Details of the letters can be found on the MOH Alert System, which is accessible via the Health Professionals Portal (HPP). HPP is a one-stop portal for all healthcare professionals in Singapore. Dentists, medical doctors and pharmacists may access HPP at https://www.moh.gov.sg/hpp/, and follow the procedures below to access the MOH Alert system.

Step 1: On the top navigation ribbon of webpage, select 'For Healthcare Professionals' followed by 'Health Professionals Portal' and click on the choice of profession. User will be redirected to the specific HPP webpage for the selected profession.

Step 2: Click on the Restricted Content icon on the left panel of webpage and login via SingPass.

Step 3: Click on the MOH Alert icon under ‘Applications’ section

Step 4: Click on the Drug Alert tab to view the DHCPLs.