Indications: 4.1.2. Focal upper limb spasticity Upper limb spasticity associated with stroke in adults aged over 18 years. 4.1.3. Lateral canthal lines (crow's feet lines) Temporary improvement in the appearance of moderate to severe lateral canthal lines (crow's feet lines) associated with orbicularis oculi muscle activity in adults below 65 years of age. 4.1.4. Blepharospasm Treatment of benign essential blepharospasm in adults aged over 18 years 4.1.5. Benign masseter muscle hypertrophy (square jaw) Temporary improvement in marked* to very marked** benign masseter muscle hypertrophy associated with conditions such as bruxism (including teeth clenching and grinding) in adults below 65 years of age. * Marked: At rest, the lower face contour, including the masseter muscle, jaw, and jawline, is square, and the surface of the masseter muscle is severely convex. At maximum clenching, the lower face contour shows a severe difference compared to at rest, and the masseter muscle mass is firm or hard and palpable. ** Very marked: At rest, the lower face contour, including the masseter muscle, jaw, and jawline, is trapezoidal, and the surface of the masseter muscle is severely convex. At maximum clenching, the lower face contour shows a severe difference compared to at rest, and the masseter muscle is hard and palpable |