Lipidem® 200mg/ml Emulsion for Infusion (10 x 500 ml): Important information on subvisual agglomerates and the need to use an infusion filter for fat emulsions

A Dear Healthcare Professional Letter has been issued by B. Braun Singapore Pte Ltd to inform healthcare professionals that subvisual droplet-like structures of emulsion components were detected in Lipidem® 200mg/ml Emulsion for Infusion (10 x 500 ml). The earliest time of the subvisual droplet-like structures of emulsion components detection was 18 months. At higher temperatures, this effect may occur earlier. Intravenous administration of the droplet-like structures can lead to adverse events such as embolism in the capillary tissue of the lungs. Healthcare professionals are advised to use the lipid emulsion filter with a pore size of 1.2 μm (Intrapur® Lipid 1.2μm infusion filter) with Lipidem® 200mg/ml Emulsion for Infusion until further notice. Please refer to the letter for details.
Healthcare professional, Industry member, Therapeutic Products
Published:

Dear Healthcare Professional Letters

3 Sep 2025

Only abstracts of the Dear Healthcare Professional Letters (DHCPL) are provided on this website. Details of the letters can be found on the MOH Alert System, which is accessible via the Health Professionals Portal (HPP), a one-stop portal for all healthcare professionals in Singapore. Dentists, medical doctors and pharmacists may access HPP at https://www.hpp.moh.gov.sg and follow the procedures below to access the MOH Alert system.

Step 1: Select your profession under 'For Healthcare Professionals’.

Step 2: Click on 'Restricted Content' and log in via SingPass.

Step 3: Click on the MOH Alert icon under ‘Applications’.

Step 4: Click on the Drug Alert tab to view the DHCPLs.