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A Singapore Government Agency Website

Recall of three metformin products found to contain NDMA

The Health Sciences Authority (HSA) would like to inform healthcare professionals about the recall of three metformin products which have been detected to contain trace amounts of N-nitrosodimethylamine (NDMA) beyond the internationally acceptable level. HSA has tested all the metformin products in the Singapore market, and found that besides these three products, none of the other 43 metformin products marketed in Singapore contain NDMA above the acceptable level. Please refer to the letter for details.
Healthcare professional, Therapeutic Products

Dear Healthcare Professional Letters

12 Dec 2019

Only abstracts of the Dear Healthcare Professional Letters (DHCPL) are provided on this website. Details of the letters can be found on the MOH Alert System, which is accessible via the Health Professionals Portal (HPP). HPP is a one-stop portal for all healthcare professionals in Singapore. Dentists, medical doctors and pharmacists may access HPP at, and follow the procedures below to access the MOH Alert system.

Step 1: On the top navigation ribbon of webpage, select 'For Healthcare Professionals' followed by 'Health Professionals Portal' and click on the choice of profession. User will be redirected to the specific HPP webpage for the selected profession.

Step 2: Click on the Restricted Content icon on the left panel of webpage and login via SingPass.

Step 3: Click on the MOH Alert icon under ‘Applications’ section

Step 4: Click on the Drug Alert tab to view the DHCPLs.