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Educational materials for healthcare professionals

Find educational materials on therapeutic products intended for healthcare professionals or directed at their patients

Overview

The educational materials listed below highlight specific safety concerns associated with the use of selected therapeutic products and provide advice on the actions required to optimise the safe and effective use of these products.

  • Physician Educational Material (PEM): Intended for use by healthcare professionals in conjunction with the approved Singapore package insert. The PEM highlights safety concerns associated with the product and their risk mitigation measures e.g. selection of the appropriate patient group, close adherence to the recommended dosing information, close monitoring for early signs of adverse events that could require therapy modification.
  • Patient Medication Guide (PMG) and Patient Alert Card (PAC): Intended for dissemination by healthcare professionals to their patients or patients’ caregivers. The PMG and PAC provide important information for patients and their caregivers regarding the use of the product e.g. self-monitoring for early signs and symptoms of adverse events, when to seek prompt medical attention.

Only HSA-approved educational materials are listed below. These materials are published with the agreement of the company responsible for producing them, and are not intended to replace medical advice offered by healthcare professionals.

Active ingredient(s) Brand name Company Educational material(s)
Agomelatine  Valdoxan Servier (S) Pte Ltd

Valdoxan PEM315 KB

Valdoxan PMG617 KB

Alemtuzumab Lemtrada Sanofi-aventis Singapore Pte Ltd

Lemtrada PEM1877 KB

Lemtrada HCP Checklist456 KB

Lemtrada PMG1662 KB

Lemtrada PAC304 KB

Ambrisentan Volibris GlaxoSmithKline Pte Ltd Volibris PMG1787 KB
Apixaban Eliquis Pfizer Private Limited Eliquis PAC511 KB
Atezolizumab Tecentriq Roche Singapore Pte Ltd Tecentriq PMG6263 KB
Avelumab Bavencio Merck Pte Ltd Bavencio_PMG224 KB
Belimumab  Benlysta GlaxoSmithKline Pte Ltd Benlysta PMG231 KB
Blinatumomab Blincyto Amgen Biotechnology Singapore Pte Ltd

Blincyto_PEM2303 KB

Blincyto PMG5345 KB

Bosentan
 
Tracleer Johnson & Johnson Pte Ltd

Tracleer PMG148 KB

Bosentan Proart  Ranbaxy (Malaysia) Sdn Bhd Proart_PMG415 KB
Clostridium Botulinum Toxin Type A Botox Allergan Singapore Pte Ltd

Botox PEM1267 KB

Botox PMG162 KB

CYD Dengue Virus Serotype 1-4 Dengvaxia Sanofi-aventis Singapore Pte Ltd

Dengvaxia PEM119 KB

Dengvaxia PMG95 KB

Dabigatran Pradaxa Boehringer Ingelheim Singapore Pte Ltd Pradaxa PAC1501 KB
Daratumumab Darzalex Johnson & Johnson Pte Ltd

Darzalex PEM_Physician810 KB

Darzalex PEM_Bloodbank1603 KB

Darzalex PAC137 KB

Deferasirox Jadenu Novartis (Singapore) Pte Ltd

Jadenu PEM1395 KB

Jadenu PMG1110 KB

Dronedarone  Multaq Sanofi-aventis Singapore Pte Ltd

Multaq PEM544 KB

Multaq PAC67 KB

Durvalumab Imfinzi AstraZeneca Singapore Pte Ltd Imfinzi PMG260 KB
Eculizumab  Soliris DKSH Singapore Pte Ltd

Paroxysmal Nocturnal Haemoglobinuria (PNH)

Soliris PEM_PNH196 KB

Soliris PMG_PNH176 KB

Soliris PAC99 KB

Atypical Haemolytic Uraemic Syndrome (aHUS)

Soliris PEM_aHUS181 KB

Soliris PMG_aHUS177 KB

Soliris PAC99 KB

Eltrombopag  Revolade Novartis (Singapore) Pte Ltd Revolade PMG1949 KB
Emicizumab Hemlibra Roche Singapore Pte Ltd

Hemlibra PMG177 KB

Hemlibra PAC128 KB

Esketamine Spravato Johnson & Johnson Pte Ltd

Spravato PEM1074 KB

Spravato HCP Checklist107 KB

Spravato PMG2308 KB

Fingolimod  Gilenya Novartis (Singapore) Pte Ltd

Gilenya PEM122 KB

Gilenya PMG955 KB

Gilenya PAC344 KB

Insulin glargine, Lixisenatide Soliqua Sanofi-aventis Singapore Pte Ltd Soliqua PEM918 KB
Ipilimumab Yervoy Bristol-Myers Squibb (Singapore) Pte Ltd Yervoy PMG91 KB
Lenalidomide Revlimid Celgene Pte Ltd

Revlimid PEM649 KB

Revlimid PMG170 KB

Macitentan Opsumit Johnson & Johnson Pte Ltd Opsumit PMG104 KB
Natalizumab Tysabri Eisai (Singapore) Pte Ltd

Tysabri PEM549 KB

Tysabri PAC93 KB

Nivolumab Opdivo Bristol-Myers Squibb (Singapore) Pte Ltd Opdivo PMG2828 KB
Pembrolizumab Keytruda MSD Pharma (Singapore) Pte Ltd Keytruda PMG68 KB
Pomalidomide Pomalyst Celgene Pte Ltd

Pomalyst PEM649 KB

Pomalyst PMG170 KB

Rivaroxaban Xarelto Bayer (South East Asia) Pte Ltd Xarelto PAC632 KB
Romiplostim  Romiplate Kyowa Kirin Asia Pacific Pte Ltd

Romiplate PEM897 KB

Romiplate PMG431 KB

Siponimod Mayzent Novartis (Singapore) Pte Ltd

Mayzent PEM180 KB

Mayzent PMG177 KB

Mayzent PAC152 KB

Trastuzumab emtansine Kadcyla Roche Singapore Pte Ltd Kadcyla PEM772 KB
Vedolizumab Entyvio Takeda Pharmaceuticals (Asia Pacific) Pte Ltd Entyvio PMG1501 KB
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